The ability to provide a conventional precision strike on time-sensitive and critical targets is of extreme importance to the DoD, as is the ability to defeat the adversaries’ hypersonic weapons. This topic is devoted to examining the various service and agency capabilities and the technologies and testing associated with achieving hypersonic velocities, advanced flight dynamics, and defeating hypersonic threats. Hypersonic cruise and glide threat vehicles present unique challenges to our defenses including very high speeds, high-G maneuvers, low detectability, exo-and endo-atmospheric flight, difficult endgame dynamics, and demanding reaction times. This Session addresses technologies, capabilities, and experimentation to defeat these threats with both hardkill and softkill techniques.